Volume 194, number 12: Human Papillomavirus Prevalence in Women Who Have and Have Not Undergone Hysterectomies
14th Nov 2006, 00:59 GMT
We compared human papillomavirus (HPV) prevalence in an age-stratified random sample of women who have undergone a hysterectomy (WH) ([FORMULA]) with the HPV prevalence in age-matched women with intact cervices (women who have not undergone a hysterectomy [WNH]) ([FORMULA]) participating in a study at Kaiser Permanente in Portland, Oregon. Testing cervicovaginal lavage fluids for >40 HPV genotypes using an MY09/11 L1 consensus primer polymerase chain reaction method, we found no statistical differences in the prevalence of HPV (16% for WNH vs. 13.9% for WH) or carcinogenic HPV (6.5% for WNH vs. 4.5% for WH) between the 2 groups of women. Although WH have a similar prevalence of carcinogenic HPV infection, compared with WNH without a cervix, they have minimal risk of HPV-induced cancer and are unlikely to benefit from HPV testing.
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