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NIAID Scientists Characterize The Most Infectious Prion Protein Particles

9th Sep 2005, 04:25 GMT

A new study of prions--apparently malformed proteins that initiate deadly brain diseases such as Creutzfeldt-Jakob disease in humans--has yielded surprising information about how the size of prions relates to their infectivity. Scientists have found that small prions are much more efficiently infectious than large ones, yet there also is a lower size limit, below which infectivity is lost.

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