How Chromosomal Leap Frog Causes Cancer In B Cells
6th Jan 2006, 23:54 GMT
MALT lymphoma is a cancer of B cell lymphocytes that usually develops in lymphatic tissues in the stomach, thyroid, lungs or eyes. At least 3 different chromosomal translocations - where parts of chromosomes are interchanged - have been implicated in the development and progression of MALT lymphoma. In a study appearing in the January 4, 2006 issue of the Journal of Clinical Investigation, Xiaolu Yang and colleagues from University of Pennsylvania School of Medicine, show how a chromosomal translocation that results in fusion of the cIAP2 region on chromosome 11 with the MALT1 gene on chromosome 21, contributes to MALT lymphoma... click link for more info.
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